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Michael Rosario

Michael Rosario

As an experienced software developer with over 13 years of experience, I enjoy helping organizations with agile software development, promoting cultures of innovation, and creative business solutions.  I enjoy helping organizations and software teams discover the craft of continuous improvement.   I am always looking for opportunities to serve leaders and teams who want to create more value with integrity, character, and predictability.

I also serve as founding member of SparkMacon MakerSpace.  SparkMacon is a community innovation space equipped with the tools, equipment, and grass-roots education required to convert your idea into a reality.   Think of it as a gym membership to exercise your creativity, hands and brain.

Professional  interests:

 

Professional Scrum Master

 

PSDI

Professional Scrum Developer I

 

Personal interests:

  • Having fun outdoors with my wife and family
  • My wife works as a college biology professor.   We have a lot of fun researching educational technology together to help engage her students.
  • Music making: playing violin, piano, guitar, MIDI sequencing, and music ministry
  • As a software engineer, I love the craft of making software and enjoy helping others accomplish their dreams using technology.

Blogs:

Contact info:

Certified Professional Scrum Master through Scrum.org

Publications

  • Amy K. Hoover, Michael P. Rosario, and Kenneth O. Stanley (2008) Scaffolding for Interactively Evolving Novel Drum Tracks for Existing Songs In: Proceedings of the Sixth European Workshop on Evolutionary and Biologically Inspired Music, Sound, Art and Design (EvoMUSART 2008). New York, NY: Springer, 2008 (10 pages) Winner of the Best Paper Award at EvoMUSART 2008 – http://bit.ly/17nays
  • Aaron McKinney, Michael Rosario, Kevin Glover. “Game Based Learning and STEM Education.”  S.T.E.M. Magazine

 

Dr. Sarah Rosario

Dr. Sarah Rosario

Education

Bachelor of Science, 2000
Biology
Florida State University, Tallahasssee FL

Master of Public Health, 2002
Environmental and Occupational Health- Tropical and Communicable Disease
University of South Florida, Tampa FL

Doctor of Philosophy, 2009
Biomedical Science
University of Central Florida, Orlando, FL

Research

Post-Doctoral Fellow – 2009-2010
Mercer University School of Medicine
Macon, Georgia

Research focused on toxin-antitoxin (TA) loci in the pathogen Haemophilus influenza. This organism is responsible for otitis media (ear infections). These TA loci are associated with the regulation of stress-induced reversible growth arrest. Research aims included the generation of recombinant strains deficient in three identified TA loci, characterization of these mutant strains under stress conditions and evaluation of the role of TA loci in pathogenesis.

Doctoral Research – 2004-2009
University of Central Florida
Orlando, Florida

Research included characterization of selenoproteins and selenium metabolism in the anaerobic microorganisms Treponema denticola and Clostridium difficile. Studies were focused on targeting selenium metabolism in the development of novel antimicrobial agents and the characterization of C. difficile toxin gene regulation in response to selenium dependent Stickland fermentation of amino acids.

Publications

Jackson-Rosario, S.E. and W.T. Self. 2010. Targeting selenium metabolism and selenoproteins: Novel avenues for drug discovery. Metallomics 2:112-116

Jackson-Rosario, S., and W. T. Self. 2009. Inhibition of selenium metabolism in the oral pathogen Treponema denticola. J Bacteriol 191:4035-40.

Jackson-Rosario, S., D. Cowart, A. Myers, R. Tarrien, R. L. Levine, R. A. Scott, and W. T. Self. 2009. Auranofin disrupts selenium metabolism in Clostridium difficile by forming a stable Au-Se adduct. J Biol Inorg Chem 14:507-19.

Ganyc, D., Talbot, S., Konate, F., Jackson, S., Schanen, B. Cullen, W., and W.T. Self (2007). Impact of Trivalent Arsenicals on Selenoprotein Synthesis. Environ Health Persp. 115(3):346-353.

Jackson, S., Calos, M., Myers, A., and W.T. Self (2006). Analysis of proline reduction in the nosocomial pathogen Clostridium difficile. J. Bacteriol. 188(24):8487-95.

Peer-Reviewed Abstracts and Meeting Presentations

S.E. Jackson-Rosario*, D.A. Daines (2010) “The vapBC-1 toxin-antitoxin locus plays a role in the adaptation of nontypeable Haemophilus influenzae to stress” 110th General Meeting of the American Society for Microbiology (ASM), San Diego, California, May 23-27, 2010.S. E. Jackson-Rosario*, C. Korsvik, A. Myers, R. Tarrien, W. T. Self (2009) “Stickland fermentation and toxin production in Clostridium difficile” 109th General Meeting of the American Society for Microbiology (ASM), Philadelphia, Pennsylvania, May 17-21, 2009. Poster B-121.S.E. Jackson-Rosario and W. T. Self* (2008) “Targeting Selenium metabolism in Stickland fermentors: Novel Narrow Spectrum Antimicrobial Drug Development” Anaerobes 2008: Ninth Biennial Congress of the Anaerobe Society of the Americas, Long Beach, California, June 24-27, 2008.S.E. Jackson-Rosario* and W. T. Self (2008) “Interruption of Selenium metabolism: A Novel pathway for Antimicrobial Development” Annual meeting of the Florida Branch of the American Society for Microbiology, Jacksonville, Florida, November 8th-9th.S.E. Jackson-Rosario, R. Tarrien, C. Korsvik, and W. T. Self* (2008)
“Selenium Availability Influences the Antimicrobial Action of Stannous Salts Against Treponema denticola” 108th General Meeting of the American Society for Microbiology (ASM), Boston, Massachusetts, June 1-5, 2008. Poster K-053.S.E. Jackson*, A. Myers, R. Tarrien and W. T. Self (2007) “Auranofin interferes with Selenium metabolism in Clostridium difficile” Florida Branch ASM meeting, St. Petersburg, Florida, October 6-8th.S.E. Jackson*, A. Myers, R. Tarrien and W. T. Self (2007) “Auranofin interferes with Selenium metabolism in Clostridium difficile” Interscience Conference on Antimicrobial Agents and Chemotherapy, (ICAAC 2007), Chicago, Illinois. Student received a $500 competitive travel awardA. Myers*, S.E. Jackson, R. Tarrien, W.T. Self (2007) “Inhibition of Clostridium difficile growth by proline derivatives and gold compounds” SURE 2007- Showcase of Undergraduate Research, April 6th, University of Central Florida, Orlando, Florida.S.E. Jackson*, Mary Calos, A. Myers and W.T. Self (2006) “Selenoproteins in Clostridium difficile: A role in pathogenesis” Selenium 2006. 8th International Symposium on Selenium in Biology and Medicine, Madison, Wisconsin.D. Ganyc*, S. Talbot, S.E. Jackson and W.T. Self (2006) “Effects of trivalent arsenicals on selenium metabolism in (HaCaT) skin cell model” Selenium 2006. 8th International Symposium on Selenium in Biology and Medicine, Madison, Wisconsin.S. Talbot*, D. Ganyc, S.E. Jackson and W.T. Self (2006) “Arsenite Inhibits Selenoprotein Synthesis in a Lung Cell Model.” Selenium 2006. 8th International Symposium on Selenium in Biology and Medicine, Madison, Wisconsin.S. E. Jackson*, A. Myers and W.T. Self (2006) “The effect of Stickland acceptors on toxin regulation in Clostridium difficile” ASM General Meeting, Orlando, Florida.S.E. Jackson*, A. Myers and W.T. Self (2006) “The effect of Stickland acceptors on toxin regulation in Clostridium difficile” Florida Branch ASM (Oral Presentation), Cocoa Beach, Florida.S.E. Jackson*, M. Calos, A. Myers, and W.T. Self (2006) “Stickland reactions in Clostridium difficile:: A role in pathogenesis?” UCF Burnett College of Biomedical Sciences Graduate Symposium (Oral Presentation)

S.E. Jackson, M. Calos and W.T. Self* (2005) Stickland Reactions and Toxin Production in Clostridium difficile. IUMS 2005- International Congress of Bacteriology and Applied Microbiology, San Francisco, California.

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